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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7760 | Thalidomide-O-amido-C3-NH2 TFA | Cereblon Ligand-Linker Conjugates 16 TFA,E3 Ligase Ligand-Linker Conjugates 52 TFA | E3 Ligase Ligand-Linker Conjugate , Ligand for E3 Ligase |
Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-C3-NH2 TFA incorporates the Thalidomide based cereblon ligand and a linker... | |||
T17874 | Nutlin carboxylic acid | MDM2 ligand 1,E3 ligase Ligand 16 | Others |
Nutlin Carboxylic Acid (MDM2 ligand 1), derived from Nutlin 3, serves as an MDM2 ligand. It can be attached to a protein ligand via a linker to create PROTACs[1]. | |||
T18555 | Pomalidomide-PEG2-Tos | Cereblon Ligand-Linker Conjugates 16,E3 ligase Ligand-Linker Conjugates 52 | Others |
Pomalidomide-PEG2-Tos is a compound that consists of an E3 ligase ligand-linker conjugate. It is composed of a cereblon ligand conjugated to a two-unit PEG linker[1]. | |||
T18872 | (S,R,S)-AHPC-PEG5-COOH | VH032-PEG5-COOH,E3 Ligase Ligand-Linker Conjugates 58,VHL Ligand-Linker Conjugates 16 | Others |
(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for use in PROTAC technology. It consists of the (S,R,S)-AHPC based VHL ligand and a 5-unit PEG linker [1]. | |||
T39609 | CIAP1 Ligand-Linker Conjugates 16 | cIAP1 Ligand-Linker Conjugates 16 | |
cIAP1 Ligand-Linker Conjugates 16 refers to a specific type of ligase ligand-linker conjugate, possessing the ability to engage with E3 ligases, which finds application in the synthesis of PROTACs. |